Posts by: Ana Pamplona, PhD

Ana Pamplona, PhD

Ana holds her PhD in Biochemistry from the Faculty of Science and Technology from Lisbon (UNL). She has worked in the T-cell differentiation and Tumor targeting Lab at Instituto de Medicina Molecular, headed by Prof. Bruno Silva-Santos, and has served as a scientific reviewer for the peer-reviewed journal Infection & Immunity.

June 23, 2017June 24, 2017

Swiss Regulators to Consider Cx601 as a Treatment for Crohn’s-related Anal Fistulas

News

Swiss regulators have agreed to review Cx601 as a treatment for Crohn’s-disease-related skin sores known as complex perianal fistulas. The Swiss Agency for Therapeutic Products, or Swissmedic, granted orphan drug status to the stem ... Read more

December 4, 2015December 4, 2015

IBD Disorders Found to Be Complex and Distinguished by Genetic Variations

News

New findings on inflammatory bowel disease (IBD) suggested that genetic variation is critical for determining disease severity and could provide a more personalized approach for clinical management of IBD patients. The ... Read more

October 16, 2015October 16, 2015

Control of HAS3 Expression in IBD Patients as a Potential Target for Drug Therapeutics

News

A recent study entitled “Hyaluronan Synthase 3 Null Mice Exhibit Decreased Intestinal Inflammation and Tissue Damage in the DSS-Induced Colitis Model” was published in the International Journal of Cell Biology ... Read more

July 31, 2015July 31, 2015

Differences in Cell-Signaling Protein Production Levels Do Not Affect Disease Type in Quiescent Crohn’s Disease

Crohn's Disease, News

A new study on Crohn’s Disease revealed that individual differences in innate cytokine production are not important in the development of Quiescent Crohn’s Disease. The study entitled “LPS-Stimulated Whole Blood Cytokine Production ... Read more

May 12, 2015September 28, 2016

Fecal Calprotectin Shown To Be Potential Biomarker for Crohn’s Disease Recurrence After Intestinal Resection

Crohn's Disease, News

New research revealed that fecal calprotectin levels may be a biomarker for assessing Crohn’s disease after intestinal resection. The study entitled ”Measurement of Fecal Calprotectin Improves Monitoring and Detection of ... Read more

April 15, 2015April 15, 2015

Chronic Inflammation and Immunosuppressive Therapy Increases IBD-associated Colorectal Cancer Risk

IBD News, News

A recent review entitled “Cancers Complicating Inflammatory Bowel Disease” described an association between the risk for several types of cancers in patients with inflammatory bowel disease due to chronic intestinal ... Read more

January 23, 2015January 23, 2015

Viruses Involved in Pathogenesis of IBD

Crohn's Disease, News, Ulcerative colitis

A recent pivotal study associates inflammatory bowel diseases, like Crohn’s disease (CD) and ulcerative colitis (UC), to changes in the variety of viruses in the gut. The study, entitled “Disease-Specific ... Read more

December 30, 2014December 30, 2014

Researchers Investigate New Treatments for Filiform Polyposis Associated with GI Issues Such as IBD

IBD News, News

A new study entitled “Diffuse filiform polyposis of the small intestine without inflammatory bowel disease” was published in the World Journal of Surgical Oncology by Jin-Wei part of Dr. Yu-Jie ... Read more

December 29, 2014December 29, 2014

Is the Gut Bacteria Associated with Crohn’s Disease and Ulcerative Colitis Inherited?

IBD News, News

A new study on inflammatory bowel disease (IBD) entitled “Complex host genetics influence the microbiome in inflammatory bowel disease” was recently published in Genome Medicine by Dr. Dan Knights from University ... Read more

December 13, 2014December 17, 2014

Study on Pathogenesis of Inflammatory Bowel Disease Reveals Promising Insights

IBD News, News

A new study on the role of Toll-like receptor 4 and the pathogenesis of inflammatory bowel disease (IBD) entitled “Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms: new data and a ... Read more