Chronic Inflammation and Immunosuppressive Therapy Increases IBD-associated Colorectal Cancer Risk

Chronic Inflammation and Immunosuppressive Therapy Increases IBD-associated Colorectal Cancer Risk
shutterstock_17868235A recent review entitled “Cancers Complicating Inflammatory Bowel Disease” described an association between the risk for several types of cancers in patients with inflammatory bowel disease due to chronic intestinal inflammation or immunosuppressive therapies. This review was published in the New England Journal of Medicine by Dr. Laurent Beaugerie from Hôpital Saint-Antoine in Paris and Dr. Steven H. Itzkowitz from Icahn School of Medicine at Mount Sinai. “Among the chronic inflammatory diseases that often require the prolonged use of immunosuppressants, [IBD] is an intriguing model because immunosuppressants may reduce the incidence of inflammation-related cancers through their anti-inflammatory effects or promote immunosuppression-related cancers,” wrote Dr. Beaugerie and Dr. Itzkowitz, in a news release. In North America and some countries in Europe, individuals with inflammatory bowel disease (IBD) and adolescents with pan colitis, a very severe form of ulcerative colitis, with the disease spreading 
Subscribe or to access all post and page content.

Leave a Comment

Your email address will not be published. Required fields are marked *