Is the Gut Bacteria Associated with Crohn’s Disease and Ulcerative Colitis Inherited?

Is the Gut Bacteria Associated with Crohn’s Disease and Ulcerative Colitis Inherited?
gut bacteriaA new study on inflammatory bowel disease (IBD) entitled “Complex host genetics influence the microbiome in inflammatory bowel disease” was recently published in Genome Medicine by Dr. Dan Knights from University of Minnesota's Department of Computer Science and Engineering and the Biotechnology Institute. In this study, Dr. Knights and colleagues found that patients with inflammatory bowel disease (IBD), such as Crohn’s disease and ulcerative colitis, can inherit the ‘gut’ bacteria that cause the pathologies. According to the Crohn’s and Colitis Foundation of America, 1.6 million Americans have Crohn’s disease or ulcerative colitis. Therefore, better knowledge of the pathogenesis of these diseases will improve their prevention and treatment. Inflammatory bowel disease (IBD) susceptibility has been associated with the interactions between host genetics and type of host-microflora in the gut. However, there has been no direct comparison between complex genome-microbiome associations in large groups of patients with an immunity-related disease. “The intestinal bacteria, or ‘gut microbiome,’ you develop at a very young age, can have a big impact on your health for the rest of your life,” said Dr. D
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One comment

  1. Anonymous says:

    Recently, researchers linked bacteria that develops from the consumption of animal products, namely meat, dairy, and eggs, to inflammatory bowel disease (IBD). When patients were placed on a plant-based diet, a diet that excludes all animal products from the diet, another type of bacteria formed that helps break down carbohydrates and starches, which helped lower inflammation. Bacteria in the GI tract changes rapidly when switching from a plant-based diet to a omnivorous diet, as certain bacteria are needed to break down carbohydrates, starches, and meat, dairy, and eggs. Unfortunately, the bacteria produced to help break down animal products has been linked to inflammation in the GI tract and throughout the body, and it has been linked to heart disease. Bacteria produced helped to break down plant matter, on the other hand, has been shown to dramatically lower inflammation.

    Hence the bad bacteria may not only form due to antibiotic usage and negative elements in the environment, but also diet; specially, diets high in animal products may lead to the development of IBD and relapse after remission is achieved. In fact, when patients with IBD were placed on a plant-based diet, 97% stayed in remission without the need for pharmaceuticals.

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