IBD News

June 16, 2016June 16, 2016

Severe Pediatric Onset IBD May See New Therapy Via Three-Part Venture

IBD News, News

Medgenics recently announced a partnership with Kyowa Hakko Kirin to develop and commercialize the company’s first-in-class anti-LIGHT monoclonal antibody for severe pediatric onset inflammatory bowel disease (IBD). Plans are in the works to begin signal ... Read more

June 14, 2016June 14, 2016

Theravance Reports Positive Phase 1 Data on TD-1473, a JAK Inhibitor for IBD

IBD News, News, Ulcerative colitis

Theravance Biopharma, Inc., recently reported positive data from its Phase 1 clinical trial assessing TD-1473, a new and oral pan-Janus kinase (JAK) inhibitor designed to enter the gastrointestinal tract and target inflammation without significant ... Read more

June 9, 2016August 12, 2016

IBD Study Shows Celltrion’s Inflectra, Biosimilar of Infliximab, Is Safe and Effective

Crohn's Disease, IBD News, News, Ulcerative colitis

Celltrion’s Inflectra, a biosimilar version of infliximab (Remicade), is both safe and effective in patients with inflammatory bowel disease (IBD), a recent study reported at the Digestive Disease Week 2016 meeting ... Read more

June 7, 2016June 7, 2016

Some Crohn’s Disease Patients Reach Remission with Risankizumab

Crohn's Disease, IBD News, News

Phase 2 clinical trial results showed that patients with moderate to severe active Crohn’s disease can achieve disease remission when treated with risankizumab, a Boehringer Ingelheim investigational biologic product. The study, “IL-23 ... Read more

June 6, 2016June 6, 2016

Insights Into Intestinal Stem Cells Could Help Improve IBD Therapies

IBD News, News

The location of intestinal stem cells and their proliferation inhibitors were recently identified in a study “The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites,” published in Cell. The findings ... Read more

May 31, 2016May 31, 2016

Two Variants of a Gut Protein Seen to Have Opposite Roles in Colitis and Colon Cancer Risk

Colon Cancer, IBD News, News, Ulcerative colitis

A team of researchers at the University of California, Riverside, found that a tight control of the levels of two forms of the same protein, hepatocyte nuclear factor 4-alpha (HNF4-α), is critical ... Read more

May 26, 2016May 26, 2016

AbbVie Showcases IBD Therapies at Digestive Disease Week Annual Meeting

Crohn's Disease, IBD News, News, Ulcerative colitis

North Chicago, Illinois based multinational biopharmaceutical company AbbVie presented 13 abstracts at the Digestive Disease Week (DDW) Annual Meeting held May 21-24, 2016, at San Diego, California. Abstracts presented addressed ... Read more

May 19, 2016May 23, 2016

Variants in ATG16L1 Gene Linked to Risk of Crohn’s Disease Through Impact on Gut Bacteria

Crohn's Disease, IBD News, News

A study found the protection against Crohn’s disease rendered by specific microorganisms in the gut might be ineffective in people who possess a variant of the ATG16L1 gene. The researchers suggested that certain ... Read more

May 17, 2016May 17, 2016

Risk of Developing IBD Can Be Predicted with Serum Biomarkers, Researchers Find

Crohn's Disease, IBD News, News, Ulcerative colitis

Findings from the PREDICTS study indicated that before symptoms appear, markers of Crohn’s disease can be detected. The new discovery may help to predict risk not only of disease development but ... Read more

May 13, 2016May 13, 2016

Gene Mutations Can Stop Good Gut Bacteria from Easing Crohn’s Disease

Crohn's Disease, IBD News, News

Crohn’s disease patients with certain gene mutations may not benefit from normally helpful bacteria in their guts, new research published in the journal Science revealed. The new insights may alter ... Read more