clinical trial

January 19, 2017

Protagonist Therapeutics Begins Phase 2b Trial of PTG-100 as Ulcerative Colitis Treatment

News

Protagonist Therapeutics has started a Phase 2b clinical trial to evaluate PTG-100, its lead candidate as a potential treatment for ulcerative colitis (UC). The multicenter, randomized, double-blind, placebo-controlled, parallel, adaptive two-stage trial ... Read more

January 18, 2017

Cellceutix Enrolls Second Group in Phase 2 Trial of IBD Therapy Brilacidin

News

Cellceutix has completed enrolling a second cohort of patients with mild-to-moderate ulcerative proctitis/ulcerative proctosigmoiditis (UP/UPS), two forms of inflammatory bowel disease (IBD), in its Phase 2 clinical trial evaluating brilacidin (PMX-30063). ... Read more

December 2, 2016December 2, 2016

1st Patient Enrolls in Phase 2 Study of Oral Therapy, OPRX-106, for Ulcerative Colitis

News

Protalix BioTherapeutics recently announced that the first patient has been enrolled in the Phase 2 clinical trial evaluating the safety, efficacy and properties of its lead drug candidate, OPRX-106, for the ... Read more

October 27, 2016October 27, 2016

Switch to Biosimilar Inflectra from Remicade Supported by Report at 2016 UEG Week

News

Phase 4 trial results were recently presented that supported switching patients from Remicade (infliximab) to its biosimilar drug Inflectra as a safe and non-inferior alternative. The results, presented at the UEG (United European Gasroenterology) Week 2016 in ... Read more

October 6, 2016October 19, 2016

First Ulcerative Colitis Patients Dosed in Phase 2a Trial of TopiVert’s New Therapy

News

The first patients have been dosed in TopiVert’s Phase 2a trial to assess the effectiveness, safety, and tolerability of TOP1288 (rectal form) for moderate to severe symptomatic ulcerative colitis. TopiVert focuses on developing narrow spectrum kinase ... Read more

October 6, 2016October 6, 2016

Clinical Trial of Potential Ulcerative Colitis Treatment Enters Next Phase

News

Theravance Biopharma announced the first dosing of a patient with moderate to severe ulcerative colitis enrolled in its Phase 1b clinical trial, which is evaluating the investigational drug TD-1473, a pan-Janus kinase (JAK) ... Read more

October 5, 2016

Entyvio’s Effect in IBD Continues After Years of Treatment

News

Takeda recently published interim data showing that Entyvio (vedolizumab) treatment continues to be beneficial for people with ulcerative colitis or Crohn’s disease, whether or not they were treated with TNF-blockers at an earlier date. ... Read more

July 22, 2016July 22, 2016

Promising New Ulcerative Colitis Therapy Revealed in COLLECT Trial Result

News, Ulcerative colitis

A research team led by Christopher Hawkey, a professor from Nottingham University Hospitals, U.K., reported promising results for a novel potential therapy for ulcerative colitis – cobitolimod. The study “Clinical effects of ... Read more

July 5, 2016July 5, 2016

Regular Yoga Practice Seen to Ease Disease Activity in Ulcerative Colitis Patients

News, Ulcerative colitis

Ulcerative colitis patients who practiced hatha yoga for 12 weeks experienced reductions in disease activity and saw significant improvements in their quality of life and mental health, according to a ... Read more

June 27, 2016June 27, 2016

MAP Infection-Associated Crohn’s Disease: RedHill Biopharma Shows Drug Potential

News

RedHill Biopharma announced the publication of a peer-review article demonstrating the potential efficacy of RHB-104 for the treatment of Mycobacterium avium subspecies paratuberculosis (MAP) infection-associated Crohn’s disease. The article was authored by researchers ... Read more