News

June 1, 2017

Janssen and Protagonist to Develop, Market PTG-200 for the Treatment of IBD

News

Janssen Biotech and Protagonist Therapeutics are partnering to develop, manufacture, and market PTG-200 as a treatment for Crohn’s disease and ulcerative colitis (UC). PTG-200 is a potential first-in-class oral IL-23R antagonist ... Read more

May 31, 2017

Low Calcium, Vitamin D Intake Place IBD Kids at Risk for Poor Bone Health

News

The majority of children and adolescents with inflammatory bowel disease (IBD) do not get enough calcium and vitamin D through the diet, which jeopardizes their bone health and other issues ... Read more

May 30, 2017

Low Expression of MDR1 Gene Links Mitochondria Function to Severe Colitis, Mouse Study Shows

News

Researchers identified a gene, known as multidrug resistance-1 (MDR1), that may underlie the most severe and incurable forms of inflammatory bowel diseases (IBD). The findings may lead to the development ... Read more

May 26, 2017May 26, 2017

Fatigue and Pain Are Most Challenging Symptoms for IBD Patients, Survey Shows

News

The often invisible symptoms of chronic fatigue and abdominal pain are what most affect the ability of inflammatory bowel disease (IBD) patients to function daily, a recent survey found. More ... Read more

May 25, 2017

New Clinical Trial to Study IBD and Graft-Versus-Host Disease in Children

IBD News, News

A new clinical trial at Seattle Children’s Hospital aims to provide doctors with information about how inflammatory bowel disease (IBD) develops in children. The goal is to find strategies for clinicians ... Read more

May 24, 2017

Miraca’s InformTx Treatment Response Platform for IBD Now Includes Testing for Inflectra

News

Miraca Life Sciences‘ InformTx testing helps doctors assess the response of patients with inflammatory bowel disease (IBD) to certain drug treatments. The company has now expanded its therapeutic drug monitoring ... Read more

May 23, 2017May 23, 2017

Shire’s SHP647 Shows Promise as Potential Ulcerative Colitis Treatment, Study Finds

News

Treatment with SHP647 (also known as PF-00547659) significantly decreased remission rates in a Phase 2 clinical trial of patients with ulcerative colitis, a type of inflammatory bowel disease (IBD). The ... Read more

May 22, 2017May 22, 2017

Switch From Remicade to Celltrion’s Biosimilar CT-P13 Safe in IBD, Clinical Trial Concludes

News

Patients with inflammatory bowel disease (IBD) may safely switch from Remicade (infliximab) to its biosimilar version CT-P13 — sold as Remsima and Inflectra — according to recently published clinical trial ... Read more

May 19, 2017

Gut Bacteria Change Can Signal That a Bowel Disease Is Developing, Study in Mice Reports

News

The mix of bacteria in the mucus lining the intestine begins changing long before symptoms of inflammatory bowel disease (IBD) show up, according to a study in mice at the University ... Read more

May 18, 2017May 18, 2017

Cd14 Gene Protects Mice Against Bowel Disease and Reduces Inflammation, Study Shows

News

The Cd14 gene protected mice against inflammatory bowel disease (IBD) by bolstering their intestinal barrier against harmful micro-organisms and reducing their gut inflammation, according to a study. Increasing the gene’s expression may ... Read more