Low Expression of MDR1 Gene Links Mitochondria Function to Severe Colitis, Mouse Study Shows

Low Expression of MDR1 Gene Links Mitochondria Function to Severe Colitis, Mouse Study Shows
Researchers identified a gene, known as multidrug resistance-1 (MDR1), that may underlie the most severe and incurable forms of inflammatory bowel diseases (IBD). The findings may lead to the development of new therapies for IBD patients. The study “MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation” was published in the journal Mucosal Immunology. The

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