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October 17, 2018October 17, 2018

MicroRNA-31 Identified as Possible Predictor for Crohn’s Disease Severity

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The levels of a molecule named microRNA-31 may serve as indicators of disease severity and progression in adults and children with Crohn’s disease (CD). “For such a clinically heterogenous [with ... Read more

October 15, 2018October 15, 2018

Allergan Announces Two Clinical Trials of Brazikumab for Crohn’s Disease and Ulcerative Colitis

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Allergan recently announced two new clinical trials to the test the efficacy of its investigational therapy, Brazikumab, for treatment of two forms of inflammatory bowel disease. The two clinical trials, INTREPID ... Read more

October 10, 2018October 10, 2018

Regen Ready to Launch Preclinical Studies on Lead Candidate RG-NAH005 as IBD Treatment

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Regen BioPharma, in collaboration with Zander Therapeutics, is preparing to launch preclinical studies on its lead candidate RG-NAH005 for inflammatory bowel disease (IBD), the company announced in a press release. ... Read more

October 8, 2018October 8, 2018

European Commission Grants Marketing Authorization to Hulio, a Humira Biosimilar, for IBD, Others

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The European commission (EC) has granted marketing authorization to Mylan and Fujifilm Kyowa Kirin Biologics for Hulio, a biosimilar to AbbVie’s Humira (adalimumab). The marketing authorization covers all indications for which ... Read more

September 26, 2018

Olorinab Eases Abdominal Pain Associated with Crohn’s Disease in Phase 2a Trial

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Olorinab, an investigational compound being developed by Arena Pharmaceuticals, significantly reduced chronic abdominal pain in patients with Crohn’s disease, according to topline results from a Phase 2a clinical trial. The findings also ... Read more

September 21, 2018September 21, 2018

Compound Derived from American Ginseng Improved Colitis Symptoms in Mouse Study

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Compound K, a byproduct of American ginseng, was seen to reduce bowel inflammation and abdominal pain in a recent study with mice. Ginseng root has been used as a food additive ... Read more

September 19, 2018September 19, 2018

Most IBD Specialists Support Continuing IBD Meds When Traveling to Areas With TB

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About two-thirds of inflammatory bowel disease (IBD) specialists worldwide support continuing IBD medications when traveling to tuberculosis (TB)-endemic areas, while about half offer pre-travel advice. The data also show that ... Read more

September 17, 2018September 17, 2018

Possible Link Found Between IBD and Risk of Thyroid Cancer, Study Reports

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Patients with inflammatory bowel disease (IBD), especially those with ulcerative colitis, may be at a higher risk of developing thyroid cancer. Use of immunosupressant drugs was also found to possibly ... Read more

September 14, 2018September 14, 2018

Azathioprine, Used to Treat IBD, Linked to Skin Cancer, Researchers Warn

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Azathioprine, used to treat inflammatory bowel disease, arthritis, and other conditions, has been linked to the development of skin cancer in a group of patients. In the study “The genomic ... Read more

September 11, 2018September 11, 2018

Fecal Microbiota Transplant May Effectively Treat IBD, but More Research Needed, Review Study Says

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Treating inflammatory bowel disease (IBD) with fecal microbiota transplant (FMT) shows potential, but longer clinical trials and more information on the best method of delivery, the risks, and the best matched ... Read more