Posts by: Jose Lopes

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Lyfebulb and UnitedHealth Group have selected the 11 finalists for their innovation challenge, which will reward the most innovative solutions to help patients with inflammatory bowel disease (IBD). These contestants ... Read more

July 2, 2018July 2, 2018

Byproduct of Cholesterol Metabolism May Activate Gut Immune Cells to Cause IBD, Study Says

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A cholesterol metabolite — a byproduct of cholesterol metabolism — triggers an abnormal immune response in inflammatory bowel disease (IBD) further aggravating such diseases, researchers found in a mouse ... Read more

June 20, 2018June 20, 2018

Patient Concerns Over Effects of IBD Therapies on Reproductive Health Not Adequately Addressed, Study Reports

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Women’s concerns over taking inflammatory bowel disease (IBD) medications during their reproductive years are not being satisfactorily addressed by physicians, according to a study that analyzed relevant social media ... Read more

May 18, 2018May 18, 2018

Mitochondrial DNA in IBD Patients A Potential Therapeutic Target, Study Suggests

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Patients with inflammatory bowel disease (IBD) have higher levels of inflammatory mitochondrial DNA (mtDNA) in the blood, which correlate with disease flare-ups and severity, a study reports. Researchers say these ... Read more

May 7, 2018May 7, 2018

Cellular Processes That May Be Target of Future IBD Therapies Revealed in Mouse Study

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Cellular processes leading to the production of inflammatory cells in the gut may help explain the development of inflammatory bowel disease (IBD) and lead to new therapies, according to ... Read more

April 13, 2018April 13, 2018

New Method to Record Vagus Nerve Activity Could Help Develop Treatments for IBD, Other Inflammatory Diseases, Study Suggests

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A new method to record signals transmitted in the vagus nerve in mice could aid research on inflammation-related disorders, such as inflammatory bowel disease (IBD). The new protocol was ... Read more

March 27, 2018March 27, 2018

An IBD Biologic Does Not Increase Woman’s Risk of Birth Problem, Study Finds

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Women who take biologics for autoimmune disorders either three months before or during their pregnancy are not at higher risk of a preterm birth or having a smaller than ... Read more

March 19, 2018March 19, 2018

TNF Inhibitors Do Not Increase Risk of Tumor Malignancy in Pediatric IBD, Study Shows

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Treatment of pediatric inflammatory bowel disease (pIBD) with tumor necrosis factor inhibitors (TNFi) does not increase the risk for malignancy, researchers report. The study with that finding, “Risk of malignancy ... Read more

January 18, 2018

Researchers Identify Immune Cells That May Prevent Fungal Initiation of IBD

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Researchers at Weill Cornell Medicine in New York suggest an impaired immune regulation of gut fungi may cause inflammatory bowel disease (IBD). The study, “CX3CR1+ mononuclear phagocytes control immunity to intestinal fungi,” ... Read more

January 12, 2018

Protagonist Obtains Third Patent for Therapy Targeting a Bowel Disease-related Protein

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Protagonist Therapeutics has obtained a U.S. patent for an inflammatory bowel disease treatment that is in clinical trials. PTG-100 inhibits a protein known as alpha-4-beta-7 integrin that is associated with IBDs. Scientists consider it ... Read more

Posts by: Jose Lopes

Jose Lopes

Finalists Announced for UnitedHealth and Lyfebulb’s IBD-related Innovation Challenge

Byproduct of Cholesterol Metabolism May Activate Gut Immune Cells to Cause IBD, Study Says

Mitochondrial DNA in IBD Patients A Potential Therapeutic Target, Study Suggests

Cellular Processes That May Be Target of Future IBD Therapies Revealed in Mouse Study

New Method to Record Vagus Nerve Activity Could Help Develop Treatments for IBD, Other Inflammatory Diseases, Study Suggests

An IBD Biologic Does Not Increase Woman’s Risk of Birth Problem, Study Finds

TNF Inhibitors Do Not Increase Risk of Tumor Malignancy in Pediatric IBD, Study Shows

Researchers Identify Immune Cells That May Prevent Fungal Initiation of IBD

Protagonist Obtains Third Patent for Therapy Targeting a Bowel Disease-related Protein

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