January 2, 2018

Defective MDR1 Gene May Promote Ileal Crohn’s Disease, Study Suggests

News

Researchers have found that the MDR1 gene helps protect immune cells from the damaging effects of bile acids in the intestine, preventing a condition known as ileal Crohn’s disease. The findings ... Read more

May 30, 2017

Low Expression of MDR1 Gene Links Mitochondria Function to Severe Colitis, Mouse Study Shows

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Researchers identified a gene, known as multidrug resistance-1 (MDR1), that may underlie the most severe and incurable forms of inflammatory bowel diseases (IBD). The findings may lead to the development ... Read more