Learning to live with a complex disease such as inflammatory bowel disease (IBD) can be complicated. Starting at the time you are diagnosed, many questions may come up. One of them could be why the disease developed inside of you in the first place. To help you learn more, here's a list of five risk factors for IBD: 1. Family history People with a family history of inflammatory bowel disease (IBD), especially with a first-degree relative, are 5 to 20 times more likely to develop it. A child of parents with IBD has a 5 percent risk while the sibling of a twin with IBD has a 70 percent chance of developing it. Non-identical twins have only 5-10 percent risk if the other has IBD. Read an article about a genetic variant associated with Crohn’s Disease.