Adding Walnuts to Diet May Help to Protect Against Ulcerative Colitis, Mouse Study Suggests

Adding Walnuts to Diet May Help to Protect Against Ulcerative Colitis, Mouse Study Suggests
Eating walnuts regularly may help to protect people against ulcerative colitis (UC), a study in mice suggests. But exactly how walnuts are metabolized and work in the colon is not fully understood. Titled "Dietary Walnut Supplementation Alters Mucosal Metabolite Profiles During DSS-Induced Colonic Ulceration," the study was published in the journal Nutrients. Walnuts contain a variety of compounds thought to have health benefits, like anti-inflammatory properties. They have the highest levels of omega-3 fatty acid, an essential fat for good health, of any tree nut. Previous studies have suggested that eating walnuts provides some protection against disorders ranging from colon cancer to heart disease to diabetes. Might these nutrient-rich nuts also have protective effects in ulcerative colitis? To find out, researchers fed mice either a standard chow diet or a diet containing up to 14% walnuts, which is the equivalent of a human eating around two ounces (56.6 grams) — between 20 and 25 walnuts — per day. After being on this diet for two weeks, the mice were treated with the ulcer-inducing chemical dextran sodium sulfate (DDS), making them a preclinical model of UC. The researchers then compared the intestines of mice fed either diet. In animals with a walnut-free diet, ulcers took up about 15% of the area of their colons. In mice fed the 14% walnut diet, the ulcer area was down to about 5%. This relationship wasn't perfectly dose-dependent — mice fed the
Subscribe or to access all post and page content.

Leave a Comment

Your email address will not be published. Required fields are marked *