Epigenetic Enzyme Found Lacking in Some Patients with Crohn’s Disease, Study Suggests

Epigenetic Enzyme Found Lacking in Some Patients with Crohn’s Disease, Study Suggests
Understanding epigenetic mechanisms — changes in gene expression that do not involve changing a gene’s DNA sequence itself — regulating intestinal health may lead to tailored inflammatory bowel disease (IBD) therapies, new research suggests. The study, “Maintenance of macrophage transcriptional programs and intestinal homeostasis by epigenetic reader SP140,” appeared in the journal Science Immunology. The SP140 gene

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