Innovative Surgical Care Plan for Crohn’s Disease Complication Appears to Improve Patient Outcomes

Innovative Surgical Care Plan for Crohn’s Disease Complication Appears to Improve Patient Outcomes
A collaborative effort between clinical physicians and surgeons has resulted in the first published surgical care plan focused on the management of septic perianal Crohn's disease (SPCD). This evidence-based care plan is described in the study “Combined Medical and Surgical Approach Improves Healing of Septic Perianal Crohn's Disease,” published in the latest edition of the Journal of American College of Surgeons. In the study, researchers from Penn State College of Medicine (PSCM) discuss the timeline of how the plan was created and the results when it was implemented at the clinic level. Patients with SPCD have infected abscesses that can develop into fistulas, open wounds that are notoriously hard to treat and are a cause of discomfort. The plan, which took more than a decade to develop, according to the study's authors, is based on results from the clinical outcomes of 114 patients. These patients all had SPCD, a significant complication that negatively impacts up to 40 percent of the Crohn's disease patients. The team reviewed each patient's chart and medical history with the aim of understanding what constitutes successful management of SPCD to make the condition more bearable, as well as identifying the clinical factors such as administration of anti-TNF medications, and genetic factors predictive of healing. Researchers defined “healing” as having a normal clinical exam and no pain for up to six months. The authors assessed specific gene variants (single nucleotide polymorphisms [SNP
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