Asian Study identifies Protective, Risk Factors Related To Inflammatory Bowel Disease

Asian Study identifies Protective, Risk Factors Related To Inflammatory Bowel Disease
In a recent study published in the journal Gut, a team of researchers conducted an Asian-Pacific population-based study and was able to identify an association between immunological, hygiene and dietary factors in childhood with an increase in the risk for developing inflammatory bowel disease. The incidence of IBD has increased dramatically over the past half century. Although more than 160 genetic risk loci have been identified that underlie disease predisposition, these loci have not completely explained the disease etiology. Striking epidemiological observations including the rising incidence in developing countries and the increased risk of disease in migrant populations implicate the importance of environmental influences on genetic predisposition. In the West, smoking represents one of the most consistently reported risk factors for Crohn's disease (CD), while data are more conflicting for other factors including appendectomy,tonsillectomy, breast feeding and antibiotic use. In the study titled “Environmental risk factors in inflammatory bowel disease: a population-based case-control study in Asia-Pacific,” Slew Ng from the Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Institute of Digestive Disease, Li Ka Shing Institute of Health Science, Chinese University of Hong Kong in China and colleagues confuted a population-based study as part of the Asia-Pacific Crohn’s and Colitis Epidemiology study (ACCESS) to evaluate the risk factors for the deve
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