clinical remission

February 8, 2017

Low Vitamin D Levels Linked to Increased Risk of UC Relapse Among Patients in Remission

News

Low vitamin D serum levels during periods of clinical remission increase the risk of relapse in patients with ulcerative colitis (UC), a new study shows. The results indicate that patients ... Read more

January 31, 2017January 31, 2017

Relapse Common in IBD Patients Who Stop Anti-TNF Therapy, But Can Take Years, Study Finds

News

Nearly half of the more than 1,000 people with inflammatory bowel disease (IBD) in clinical remission had a relapse some three years after stopping anti-tumor necrosis factor (anti-TNF) treatment — and more than half relapsed ... Read more

May 27, 2016May 27, 2016

Crohn’s Disease Patients See Promising Results in Stelara (Ustekinumab) Phase 3 Clinical Studies, Janssen Reports

News

Janssen Research & Development drug candidate Stelara (ustekinumab) demonstrated positive results in the IM-UNITI maintenance study investigating clinical remission effects in patients with moderate to severe Crohn’s disease. The results showed that ... Read more

April 28, 2016April 28, 2016

New Clinical Trial Data on Crohn’s Disease Treatment Filgotinib Reported by Galapagos

News

Beglium-based Galapagos NV recently reported additional data from its Phase 2 FITZROY clinical trial assessing filgotinib, a selective JAK1 inhibitor being investigated for the treatment of Crohn’s disease. The FITZROY trial assessed the efficacy and ... Read more

March 16, 2016September 28, 2016

Ulcerative Colitis IND Trial Application Cleared by FDA for InDex’s Cobitolimod

IBD News, News, Ulcerative colitis

The U.S. FDA has cleared InDex Pharmaceuticals AB’s Investigational New Drug (IND) application to launch a Phase 2b clinical trial for cobitolimod (Kappaproct) in patients with moderate to severe ulcerative colitis (UC). ... Read more

March 10, 2016March 10, 2016

Use of Glutamine in Crohn’s Disease Needs More Evaluation, Review Finds

News

A review published by the The Cochrane Library reported that there is not enough evidence to draw conclusions about the efficacy and safety of glutamine for inducing remission in patients with Crohn’s ... Read more

February 16, 2016February 16, 2016

Ulcerative Colitis Patients Resistant to Treatment May Find Golimumab a Viable Therapeutic Option

IBD News, News, Ulcerative colitis

Golimumab (symponi) is the latest addition to TNF-α blocking drugs for inflammatory bowel diseases (IBD) such as ulcerative colitis (UC). A summary of all available safety and efficacy data on the ... Read more

December 2, 2015May 17, 2016

Immune Pharmaceuticals Initiates Phase 2 Clinical Trial with Bertilimumab for Ulcerative Colitis Treatment

News, Ulcerative colitis

Immune Pharmaceuticals, Inc. recently announced the enrollment of the first patient in its Phase 2 clinical trial to assess the safety and efficacy of the first-in-class, entirely human monoclonal antibody bertilimumab for ... Read more

November 20, 2015November 20, 2015

Successful Remission in Ulcerative Colitis Patients Achieved Using Combination Therapy

News

In a new study entitled “Combination Therapy With Adalimumab Plus Intensive Granulocyte and Monocyte Adsorptive Apheresis in Patients With Refractory Ulcerative Colitis,” a team of researchers investigated if a combined ... Read more