News

August 24, 2017August 25, 2017

Takeda Asks Japanese Regulators to Approve Vedolizumab as an Ulcerative Colitis Treatment

News

Takeda Pharmaceutical Company has submitted a new drug application to Japanese regulators for vedolizumab (MLN0002) as a treatment for adults with moderate to severe ulcerative colitis. Ulcerative colitis “is a chronic, ... Read more

August 17, 2017August 18, 2017

Measuring Fecal Calprotectin Improves IBD Diagnosis in Children, Study Shows

Crohn's Disease, News

Researchers have found the fecal calprotectin test improves correct diagnosis of inflammatory bowel disease (IBD) in children, and is even more effective than blood test markers. The study, “Use of Laboratory Markers ... Read more

August 17, 2017August 18, 2017

Chronic Illness in Young People Linked to Higher Attempted Suicide Rates, Study Shows

Crohn's Disease, News

Young people between 15 and 30 years of age who live with a chronic illness, such as an inflammatory bowel disease (IBD), were found to be three times more likely ... Read more

August 16, 2017August 16, 2017

Study Dismisses Concerns that Psoriasis Treatment Could Trigger IBD

Crohn's Disease, News

Taltz (ixekizumab), an approved antibody treatment for plaque psoriasis, targets a cytokine that is thought to play a role in the development of inflammatory bowel disease (IBD). That connection has caused ... Read more

August 14, 2017August 18, 2017

NIH Unit Awards Georgia Researchers $1.4 Million to Study Novel IBD Therapies

Crohn's Disease, News

Researchers at Georgia State University’s Institute for Biomedical Sciences won a $1.4 million federal grant to study novel therapeutic approaches to treat inflammatory bowel diseases (IBDs). IBDs like ulcerative colitis and Crohn’s disease are chronic, ... Read more

August 11, 2017August 16, 2017

Ulcerative Colitis Investigational Therapy TD-1473 Shows Encouraging Results in Early Trial

News, Ulcerative colitis

Early data from a Phase 1b clinical trial show that the investigational therapy TD-1473 for patients with ulcerative colitis (UC) has demonstrated targeted action and effectiveness, according to the therapy’s ... Read more

August 11, 2017August 21, 2017

Drop in Levels of Specific Enzyme Seen to Favor Development of Pro-Inflammatory T-Cells

Crohn's Disease, News

Low levels of the enzyme PTPN2 promote the development a group of T-cells with pro-inflammatory properties, contributing to syndromes such as Crohn’s disease, scientists report. Their findings suggest that treatments targeting PTPN2 may help ... Read more

August 10, 2017October 9, 2017

Market Survey Shows Potential of JAK Inhibitors to Treat IBD

Crohn's Disease, News

Directors from pharmaceutical and health insurance companies and gastroenterologists in the United States have expressed a positive opinion overall about the use of janus kinase (JAK) inhibitors for the treatment of ... Read more

August 10, 2017August 18, 2017

Psoriasis Patients in Phase 1 Trial Receiving KY1005-CT01, a Potential Bowel Disease Therapy

Crohn's Disease, News

A 24th psoriasis patient has received KY1005-CT01 in a Phase 1 clinical trial of the treatment designed to fight the autoimmune disorder affecting the skin and other organs. KY1005 has the ... Read more

August 7, 2017August 18, 2017

Autophagy Process Essential for Normal Intestinal Defense Against Bacteria, Study Finds

Crohn's Disease, News

Researchers at UT Southwestern Medical Center found that a cellular mechanism called autophagy is an important participant in the protection of mouse intestines from inflammation triggered by invading bacteria. These ... Read more