News

October 27, 2017October 27, 2017

Innovation Readies Next Clinical Phase for Investigational IBD Therapy Brilacidin

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Innovation Pharmaceuticals, a clinical-stage biopharmaceutical company, issued an update on its research program for Brilacidin, an investigational non-corticosteroid and anti-inflammatory therapy for inflammatory bowel disease (IBD). The company is planning ... Read more

October 26, 2017October 26, 2017

Researchers Identify Protein Involved in IBD Development

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Researchers have found a protein called CCDC88B that is present at high levels in the colons of patients with inflammatory bowel disease (IBD). They suggest that this protein plays a ... Read more

October 25, 2017

Celgene Drops GED-0301 as Crohn’s Therapy but Will Continue Testing It for Ulcerative Colitis

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Celgene Corporation is giving up on GED-0301 as a Crohn’s disease therapy, but will continue to evaluate its ability to treat ulcerative colitis. It ended its Phase 3 REVOLVE clinical trial (NCT02596893) and ... Read more

October 24, 2017October 24, 2017

TiGenix Potential Therapy for Crohn’s-related Perianal Fistulas Gets FDA Approval

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The U.S. Food and Drug Administration (FDA) has granted TiGenix orphan drug designation for its lead candidate Cx601, which aims to treat perianal fistulas caused by Crohn’s disease in patients who have ... Read more

October 23, 2017

Engineered Protein ACT-101 Shows Potential in Mouse Model of Colitis, Study Shows

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Researchers have found that Alpha Cancer Technologies‘ ACT-101, an engineered protein similar to the human alpha fetoprotein (hAFP), can protect mice from developing bowel inflammation. This finding resulted from a ... Read more

October 20, 2017October 20, 2017

Ozanimod Results Promising in Crohn’s Disease, Ulcerative Colitis, Phase 2 Trial Data Show

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Celgene recently presented positive data from two Phase 2 studies — the STEPSTONE and TOUCHSTONE studies — for the company’s investigational compound ozanimod (RPC-1063) as a therapy for Crohn’s disease and ulcerative colitis ... Read more

October 19, 2017

Rise in IBDs Likely in Developing Countries, Study Predicts

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Researchers have found that the prevalence of inflammatory bowel disease (IBD) in developing countries is likely to rise over the next several years. The study “Worldwide incidence and prevalence of ... Read more

October 18, 2017

Entyvio Eased Early Symptoms of Ulcerative Colitis and Crohn’s, New Analysis Shows

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Entyvio (vedolizumab) alleviated some of the early symptoms of patients with moderate to severe ulcerative colitis and Crohn’s disease, a new analysis of Phase 3 trial results indicates. Takeda Pharmaceutical presented the ... Read more

October 17, 2017

Rectal Therapy with Prograf Helped Patients with Resistant UC, Study Shows

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Patients with resistant ulcerative proctitis, a mild form of ulcerative colitis (UC), respond to therapy with rectal Prograf (tacrolimus) ointment, achieving clinical remission and mucosal healing, according to the results of ... Read more

October 16, 2017

Breastfeeding Lowers Infant’s Risk of Developing Bowel Disease Later, Study Reports

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People who were breastfed are at lower risk of developing inflammatory bowel disease than those who weren’t, Massachusetts General Hospital researchers reported. The team said the protective effects applied to people across ... Read more