News

September 10, 2018September 10, 2018

Pliant Partners with Cleveland Clinic to Find New Disease Targets for Gut Fibrosis

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Pliant Therapeutics is starting a multi-year research collaboration with Cleveland Clinic to speed the discovery of new druggable targets for gastrointestinal fibrosis, a common gut complication in patients with inflammatory ... Read more

September 7, 2018September 7, 2018

Lindgren Score Best Predicts Response to Steroid Therapy in Acute Ulcerative Colitis Patients, Study Finds

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The Lindgren score is the best for predicting the response to intravenous steroid therapy and the need for rescue therapy or bowel surgery in patients hospitalized with acute severe ulcerative ... Read more

September 5, 2018September 5, 2018

Investigational ABX464 Enhances Remission Rates, Mucosal Healing in Ulcerative Colitis Patients in Phase 2a Trial

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Abivax‘s small, anti-inflammatory molecule ABX464 significantly increased clinical remission and mucosal healing over placebo in patients with moderate to severe active ulcerative colitis resistant to other therapies, top-line results from a ... Read more

August 31, 2018August 31, 2018

Patients with Inflammatory Bowel Disease More Likely to Develop Influenza, Study Shows

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Patients with inflammatory bowel disease (IBD) are more likely to develop influenza compared to people without IBD, a study shows. The study, “Increased Risk of Influenza and Influenza-Related Complications Among ... Read more

August 29, 2018August 29, 2018

Researchers Identify Stool Proteins that Could Help Predict IBD

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Researchers in the U.S. have made an important discovery that may soon help to identify inflammatory bowel disease (IBD) earlier and predict its behavior, which could benefit treatment. Chandra Mohan, a researcher ... Read more

August 27, 2018August 27, 2018

British Columbia Adds Renflexis, a Remicade Biosimilar for Crohn’s, UC, to Public Drug Plan

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Renflexis (infliximab-abda), Merck’s biosimilar of Remicade (infliximab), has been added to the public drug plan of the Canadian province of British Columbia. As of Aug. 21, adults and children with Crohn’s ... Read more

August 24, 2018August 24, 2018

Eating Strawberries Reduces Colon Inflammation, Improves Gut Health in IBD Mouse Model

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Less than a cupful of whole strawberries a day led to a significant decrease in colon inflammation and reversal of the pro-inflammatory gut microbiome in a mouse model of inflammatory ... Read more

August 22, 2018August 22, 2018

Healthcare Workers with IBD at Higher Risk of Tuberculosis but Not Other Infections, Study Suggests

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Healthcare workers with inflammatory bowel disease (IBD) develop tuberculosis at a higher rate than non-healthcare workers with IBD, but this trend does not extend to other types of severe infection, ... Read more

August 20, 2018August 20, 2018

Remicade at Higher Than Usual Doses Seen as Effective and Safe in Controlling Inflammation in IBD Patients

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Higher doses of Remicade (infliximab) can ease the symptoms of inflammatory bowel disease (IBD) by better controlling inflammation with raising the risk of adverse effects — like more infections — in patients, ... Read more

August 13, 2018August 13, 2018

Crohn’s and Colitis Canada Grants $2.7M to Nine IBD Researchers

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Crohn’s and Colitis Canada has awarded $2.7 million in grants to support nine Canadian researchers studying inflammatory bowel disease (IBD). The grants include seven Grants-in-Aid of Research, intended to advance prevention, ... Read more