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April 13, 2020April 13, 2020

Etrasimod in Controlled Release Seen to Limit Heart Rate Changes, May Be Added to Trials

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A controlled-release version of etrasimod could limit the changes in heart rate linked to an initial dose of this investigational medication, according to topline clinical trial data announced by ... Read more

April 6, 2020April 6, 2020

Scientists Identify Biomarkers, Environmental Factors That May Lead to IBD Prevention

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Researchers at Mount Sinai have identified new protein biomarkers of Crohn’s disease, and environmental factors that may increase a person’s risk of developing inflammatory bowel disease (IBD). Together, these ... Read more

March 30, 2020March 30, 2020

Gut Bacteria Adapt Their Behavior Depending on Where They Reside, Mouse Study Suggests

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Bacteroides fragilis, bacteria known for their protective role in the gut, change their gene activity and behavior according to where in the gut they reside, a study in mice ... Read more

March 23, 2020March 23, 2020

Infliximab Helps Gut Microbiome in Children with Crohn’s, Study Finds

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Treatment with infliximab helps normalize the gut microbiome, soothing Crohn’s disease in children and adolescents, a study suggests. Longer studies are needed to understand if these medicines can fully ... Read more

March 20, 2020March 20, 2020

Algorithm Seen to Judge Colonoscopies, Predict UC Remission with High Accuracy

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A new artificial intelligence (AI) algorithm evaluates colonoscopy exams with a level of accuracy equivalent to experts, scientists in Japan report. The AI algorithm they developed may also help ... Read more

March 18, 2020March 18, 2020

Data from Abivax Trial Testing ABX464 Anti-inflammatory for UC Expected by Year’s End

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Top-line data from an international Phase 2b clinical trial evaluating ABX464, Abivax’s lead therapeutic candidate for moderate-to-severe ulcerative colitis (UC), are expected later this year, according to the company’s ... Read more

March 16, 2020March 16, 2020

Immunosuppressive Therapy Does Not Increase Vaginal Cancer Risk, Study Finds

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Therapies that suppress the immune system do not increase the risk of vulvar or vaginal cancer in women with inflammatory bowel disease (IBD), a new study has found. The ... Read more

March 13, 2020March 13, 2020

Inflammation Type Linked to Flares, Hospitalizations in IBD Patients, Study Says

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People with inflammatory bowel disease (IBD) whose gut inflammation is driven by eosinophils — a type of white blood cells — are less likely to experience disease flares and ... Read more

March 11, 2020March 11, 2020

In $94M Agreement, Royalty Pharma Acquires Royalty Interest in Entyvio

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Royalty Pharma has bought Massachusetts General Hospital’s (MGH) royalty interest in the inflammatory bowel disease (IBD) therapy Entyvio (vedolizumab) for $94 million. Produced by Millennium Pharmaceuticals, which is part of ... Read more

March 9, 2020March 9, 2020

Osteoporosis Twice as High in IBD Patients, Danish Study Finds

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The risk of osteoporosis is twice as high in people with inflammatory bowel disease (IBD) as in the general population, a Danish study found. The study, “Incidence, risk factors ... Read more