Prometheus and Takeda Collaborate on Development of Targeted IBD Therapies

Prometheus and Takeda Collaborate on Development of Targeted IBD Therapies
Biopharmaceutical company Prometheus Biosciences is collaborating with pharmaceutical firm Takeda to discover, develop, and commercialize a new generation of targeted therapies for inflammatory bowel disease (IBD). The global, multi-target strategic collaboration will combine Prometheus’s proprietary bioformatics discovery platform and diagnostic tools with Takeda’s gastroenterology and drug development expertise in an effort to discover and advance up to three targeted IBD treatments and companion diagnostic tools. The agreement calls for Takeda to make an initial payment to Prometheus of an undisclosed amount. Prometheus also may receive up to $420 million in development, regulatory, and commercial milestone payments across the three programs. That would be in addition to royalty payments on each program’s international sales. The charge for Prometheus is to identify and validate the unique IBD therapy targets, and take on the development and commercialization of complementary diagnostics. For its part, Takeda will handle treatment discovery, clinical development, and all commercialization activities. “We are impressed with Takeda’s commitment to developing a portfolio of therapies to address all IBD patients, especially those with unmet needs,” said Mark McKenna, Prometheus CEO, in a
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