Program to Examine Gut Microbiota’s Role in Predicting Response to Therapies

Program to Examine Gut Microbiota’s Role in Predicting Response to Therapies
uBiome launched a research collaboration program with clinicians from the University of Louisville in Kentucky to investigate the usefulness of the gut microbiome to predict the clinical response of patients with inflammatory bowel disease (IBD) to certain therapies, especially biologic agents such as Entyvio (vedolizumab) or Stelara (ustekinumab). The partnership involves two physicians: Gastroenterology Fellow and founder of the IBDWatch website, Brandon Wuerth, MD; and Director of the University of Louisville Inflammatory Bowel Disease Center, Professor and Director of the Inflammatory Bowel Disease Program at the University of Illinois, Gerald Dryden, MD, PhD. "This study has the potential to inform a more personalized approach to IBD treatment and to improve outcomes. We are proud to support Wuerth and Dryden’s mission to uncover the associations of the microbiome in clinical response to therapies for IBD," Dr. Jessica Richman, co-founder and CEO of uBiome, said in a press release. The idea is that if bacteria living in the gut — the so-called gut microbiome — are able to estimate how a patient with IBD will respond to a specific medication, then
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