Abivax to Present Results of Trials of ABX464 as Ulcerative Colitis Therapy

Abivax to Present Results of Trials of ABX464 as Ulcerative Colitis Therapy
Abivax will present the complete results of its Phase 2a trial ABX464-101 (NCT03093259) and interim results of the open-label extension study ABX464-102 (NCT03368118). Both aimed to assess the safety and efficacy of ABX464 as a treatment for ulcerative colitis. The data will be presented at the 14thCongress of the European Crohn’s and Colitis Organization (ECCO) March 6-9 in Copenhagen, Denmark. The oral presentation is titled "ABX464 is safe and efficacious in a proof of concept study in ulcerative colitis patients." "We are very pleased that our abstract has been selected as a plenary presentation by ECCO’s scientific program committee,” Jean-Marc Steens, chief medical officer of Abivax, said in a press release. “This is a great scientific validation of the importance of these data and we are eager to share these promising results with the medical community, including many key [inflammatory bowel disease] specialists who may be interested to participate in our upcoming Phase 2b clinical trial.” Ulcerative colitis is an inflammatory disease that causes ulcerations on the rectum and colon. For many patients, there are limited treatment options. ABX464 is a small molecule first developed to reduce viral load in HIV-positive people. However, it also sh
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