Protagonist Halts Clinical Trial of PTG-100 for UC After Analysis Finds Study Futile

Protagonist Halts Clinical Trial of PTG-100 for UC After Analysis Finds Study Futile
A Phase 2b trial of PTG-100, an investigative therapy for moderate-to-severe ulcerative colitis (UC), has been discontinued after an interim analysis deemed the study futile, according to Protagonist Therapeutics. The randomized, double-blind Phase 2b PROPEL trial (NCT02895100), initiated in 2016, was evaluating the safety and efficacy of three daily doses of oral PTG-100 (150 mg, 300

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