Migration and Race May Play a Role in the Development of IBD

Migration and Race May Play a Role in the Development of IBD
A recent review suggests that migration and race influence the risk of developing inflammatory bowel disease. In particular, South Asian migrants have a consistently higher incidence of ulcerative colitis and a lower incidence of Crohn’s disease, researchers have found. The review titled, “Epidemiology of inflammatory bowel disease in racial and ethnic migrant groups,” was published in the World Journal of Gastroenterology. Ulcerative colitis (UC) and Crohn’s disease (CD) comprise a chronic inflammatory condition known as inflammatory bowel disease (IBD). While the cause is unknown, it is thought to emerge as an exaggerated immune response to various stimulations by the gut microbiome. IBD tends to develop in people who are genetically susceptible. Some studies have reported that migrants who move away from countries with low incidence to countries with high incidence of theses diseases tend to change and exhibit the disease prevalence of the adopted country. This is interesting as it implies there may be an environmental trigger for the diseases. So, European researchers sought to summarize the current literature and define patterns of disease in migrant and racial groups. Thirty-three studies on incidence, prevalence and disease phenotype of migrants and races, compared with indigenous groups, were eligible for inclusion in the review. "Migrants" is a term that refers to people who move to a new country as a first generation, or second generation when born there. The term "race" classifies people biologically according to physical characteristics. Sifting through the Individual studies, researchers found there w
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