Salt-inducible Kinases May Be Promising Therapeutic Targets for Crohn’s, Other Autoimmune Diseases

Salt-inducible Kinases May Be Promising Therapeutic Targets for Crohn’s, Other Autoimmune Diseases
Salt-inducible kinases (SIK) may be a novel therapeutic target for inflammation in autoimmune diseases such as Crohn's disease, psoriasis, and arthritis, according to a report published in the Journal of Leukocyte Biology, titled "SIK inhibition in human myeloid cells modulates TLR and IL-1R signaling and induces anti-inflammatory phenotype." Macrophages are cells from the innate immune system that can perform multiple tasks, such as host defense, tissue repair, and resolve inflammation, depending on their activation state. Macrophages can be activated towards a pro-inflamma
Subscribe or to access all post and page content.

Leave a Comment

Your email address will not be published. Required fields are marked *