News

May 22, 2019May 22, 2019

Helmsley Charitable Trust Grants $1.8 Million Toward Crohn’s Disease Research

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The Leona M. and Harry B. Helmsley Charitable Trust has donated $1.8 million for the development of a gut-mimicking microdevice to help scientists better understand Crohn’s disease and develop new therapies. The technology ... Read more

May 14, 2019May 14, 2019

Panaxia and Rafa Join with PlantEXT to Develop Cannabis Suppositories for IBD

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Two Israeli pharmaceutical companies are collaborating with a medical cannabis company to develop what’s being touted as the first medical cannabis rectal suppositories specifically targeted to inflammatory bowel disease (IBD) ... Read more

May 10, 2019May 10, 2019

Canada the First to Approve Phase 2b Trial of Abivax’s ABX464 for Ulcerative Colitis

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Canada has become the first country to fully authorize a Phase 2b clinical trial that will explore Abivax‘s lead candidate ABX464 in patients with ulcerative colitis, the company announced. ABX464 ... Read more

April 29, 2019April 29, 2019

Provention Bio’s Crohn’s Disease Trial is Fully Enrolled, with Top-line Results Expected Later in Year

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Provention Bio has completed patient enrollment for a Phase 2a clinical trial evaluating the efficacy and safety of its investigational oral therapy — PRV-6527 — for moderate to severe Crohn’s ... Read more

April 26, 2019April 26, 2019

New National Surveys on Medicinal Cannabis Use for IBD Symptoms Launched in Australia

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Two new national surveys on the use of cannabis for the treatment of patients with inflammatory bowel disease (IBD) have been launched in Australia. The anonymous surveys — one designed ... Read more

April 23, 2019April 24, 2019

OSE-127 Therapy Candidate Prevents Gut Inflammation by Immune Cells, Study Reports

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OSE Immunotherapeutics’ therapeutic candidate OSE-127 for chronic inflammatory bowel disease (IBD) showed anti-inflammatory activity in a study performed in mice and patients’ samples. The study, “IL-7 receptor influences anti-TNF responsiveness ... Read more

April 22, 2019April 22, 2019

Trust Grants $4.3 Million for Anti-fibrotic Research in Crohn’s Disease

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To foster the development of tools to test new anti-fibrotic treatments in Crohn’s patients, the Leona M. and Harry B. Helmsley Charitable Trust has awarded $4.3 million to three medical ... Read more

April 17, 2019April 17, 2019

Entyvio Improves Quality of Life, Work Productivity of Ulcerative Colitis Patients, Phase 3 Study Shows

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Treatment with Entyvio (vedolizumab), delivered into the blood or under the skin, led to significant clinical improvements and in quality of life, as well as work productivity in patients with moderate-to-severe ... Read more

April 15, 2019April 15, 2019

Scientists Create World’s Largest Collection of Sequenced Gut Bacteria

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An international research team has sequenced and archived the world’s most comprehensive collection of human gut bacteria, identifying a total of 105 new species of bacteria that naturally populate the ... Read more

April 10, 2019April 10, 2019

UC Candidate Therapy PL-8177 Shows Successful Delivery to Lower GI Tract

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Use of an oral, delayed-release formulation of the ulcerative colitis treatment candidate PL-8177 led to targeted delivery to the lower gastrointestinal tract and was well-tolerated, according to top-line results of ... Read more