Mice Exposed to High-Sugar Diet More Susceptible to IBD, Especially Colitis, Study Shows

Mice Exposed to High-Sugar Diet More Susceptible to IBD, Especially Colitis, Study Shows
A high-sugar diet may increase susceptibility to inflammatory bowel diseases (IBD), and specifically colitis, a study in mice suggests. Titled “A high-sugar diet rapidly enhances susceptibility to colitis via depletion of luminal short-chain fatty acids in mice,” the study was published in the journal Scientific Reports. Although the importance of diet in the development of inflammatory bowel disease (IBD) remains unclear, dietary factors do appear to play a role in triggering disease flares. Researchers at the University of Alberta were particularly interested in the impact of a “western diet” — a diet high in fat and refined sugars — on IBD. To date, most studies that have investigated the impact of a western diet on IBD have focused on either a high-fat diet alone or a high-fat diet in combination with high sugar. Therefore, the isolated effect of a high-sugar diet on IBD is not well-understood. To learn more, the researchers set out to investigate the impact of short-term dietary exposure to high sugar on a person's susceptibility to colitis, one of the two major forms of IBD. The inv
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