Non-invasive Test for Leaky Gut Could Help Diagnose IBD, Study Says

Non-invasive Test for Leaky Gut Could Help Diagnose IBD, Study Says
A novel test that measures the concentration of gut bacterial products in a person's blood and stool may become a non-invasive and risk-free way to diagnose inflammatory bowel disease (IBD), a proof-of-concept study has found. The findings were described in the study "Inflammatory bowel disease associates with increased gut‐to‐blood penetration of SCFA: A new, noninvasive marker of a functional intestinal lesion " and published in the journal Experimental Physiology. Diagnosing and monitoring IBD is typically based on a colonoscopy, which is an invasive technique that often requires anesthesia, and is suitable to assess structural lesions, rather than gut malfunction. In their study, a team of researchers from the Medical University of Warsaw, Poland, proposed the use of a marker of gut permeability as a non-invasive test to assess gut function, and to help screen and monitor the treatment of intestinal diseases. "This may be a very important tool for diagnosis and treatment of gut and other diseases, using the leaky gut as a marker for disease, as well as a potential target for treatment," Marcin Ufnal, MD, PhD, senior author of the study, said in a press release. The test requires a small sample (1 milliliter) of blood and stool, and measures the concentration of gut bacterial prod
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