Youngsters Diagnosed with IBD Have Increased Cancer Risk, Study Contends

Youngsters Diagnosed with IBD Have Increased Cancer Risk, Study Contends
Inflammatory bowel disease (IBD) diagnosis during childhood or adolescence may be linked with an increased risk for developing cancer, compared to the general population, according to results of a Danish and Finish population-based study. The study “The incidence of cancer and mortality in paediatric onset inflammatory bowel disease in Denmark and Finland during a 23‐year period: a population‐based study” was published in the journal Alimentary Pharmacology & Therapeutics. Whether IBD increases the risk for colorectal cancer has been debated for a long time, with studies reporting different results. Very few, however, have looked into the association between pediatric onset of IBD and the risk for cancer. The only two population-based studies done until now have reported an increased risk for colorectal cancer. A group of researchers at the Copenhagen University Hospital performed a retrospective analysis of data from a population-based registry in Denmark and Finland  to assess the estimated risk of cancer and mortality for early IBD. The analysis included IBD patients diagnosed before turning 18 years old from January 1992 to December 2014. In the 23-year period, researchers identified a total of 6,689 patients with pediatric onset of IBD — 3,333 in Denmark, and 3,357 in Finland. Patients' mean age at diagnosis was 14 years and were followed for a median of 9.6 years. During follow-up, 720 patients underwent surgery to remove the colon (a  colectomy). The surgery was done on average within 2.8 years of the IBD diagnosis. A total
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