Cell Therapy for Crohn’s Disease Fares Well in Preclinical Study; Clinical Trial is Next

Cell Therapy for Crohn’s Disease Fares Well in Preclinical Study; Clinical Trial is Next
An experimental cell therapy for Crohn's disease that involves taking the patient’s white blood cells, restoring their proper functioning in the lab, and giving them back to the patient, has proven effective in a preclinical study. Based on the positive results obtained in human cells growing in the lab, a clinical trial testing the treatment’s safety and effectiveness in patients is planned for the upcoming months. The study “Correction of Defective T-regulatory Cells From Patients With Crohn’s Disease by Ex Vivo Ligation of Retinoic Acid Receptor Alpha” was conducted by researchers at the Guy's and St Thomas' NHS Foundation Trust and King's College London Biomedical Research Centre (BRC). It was published in the journal Gastroenterology. Many human and animal studies have supported a key role for regulatory T cells (Tregs)  in the development of inflammatory
Subscribe or to access all post and page content.

Leave a Comment

Your email address will not be published. Required fields are marked *