Eli and Edythe Broad Foundation Awards $1.2 Million to Four UCLA Researchers in IBD

Eli and Edythe Broad Foundation Awards $1.2 Million to Four UCLA Researchers in IBD
Four UCLA researchers conducting early-stage research into inflammatory bowel disease have received four three-year grants totaling $1.2 million from the Eli and Edythe Broad Foundation. The grants bring to more than $7 million the foundation’s support for UCLA’s IBD Research Center. The recipients are:
  • Dr. Hon Wai Koon, an associate professor of medicine. He will test a bacteria-fighting peptide, or protein component, that could help ease intestinal scarring, a common complication of IBD that there are no effective treatments for.
  • Dr. Jill May Hoffman, an assistant professor of medicine. She will explore how the enteric nervous system, which scientists call the body's second brain, can promote wound healing and remission of IBD.
  • Dr. Ka Man Law, an assistant professor of medicine. He will look at a protein's role in regulating intestines' permeability, which causes loss of nutrients. The goal is to identify a genetic mechanism that an IBD treatment can target.
  • Dr. Kai Fang, an assistant project scientist. He will investigate how IBD develops, starting with  microRNAs' role in genes' production of protein. He will also look at the role that molecules called neuropeptides, which help neurons communicate with each other, play in the genes' regulation.
“More than 5 million people around the world struggle with inflammatory bowel disease,” Gerun Riley, president of the Broad Foundation, said in a
Subscribe or to access all post and page content.