Kids with IBD More Likely to Get Cancer, Swedish Study Shows

Kids with IBD More Likely to Get Cancer, Swedish Study Shows
Children with inflammatory bowel disease (IBD) face a higher risk of cancer later in life, a Swedish study has concluded. The study, “Childhood onset inflammatory bowel disease and risk of cancer: a Swedish nationwide cohort study 1964-2014,” appeared in the journal BMJ. It found that such children have a higher incidence of gastrointestinal cancers, lymphoid neoplasms and skin cancer, both during childhood and adulthood. Scientists already know that adults with ulcerative colitis and Crohn’s disease are more at risk of developing colorectal cancer. Other factors such as family history of colorectal cancer and concomitant primary sclerosing cholangitis — a chronic liver disease — are also associated with cancer in patients with adult-onset IBD. Yet little evidence supports a link between childhood-onset IBD and cancer risk. A research team led by pediatric gastroenterologist Ola Olén of Sachs’ Children and Youth Hospital in Stockholm, analyzed clinical data gathered from the Swedish National Patient Register from 1964 to 2014. The list included 9,405 patients with childhood onset IBD. Following these patients until the age of 27, researchers found that those with childhood IBD were 2.2 times more likely to develop cancer than people of similar age and gender who did not have bowel diseases. Patients with diagnosed ulcerative colitis during childhood were 2.6 times more likely, and those with Crohn’s disease had 1.7 times more likely to get cancer later in life, researchers found. Colorectal, s
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