Treatment Ends in Trial Showing That Brilacidin Is Effective Against Bowel Disease

Treatment Ends in Trial Showing That Brilacidin Is Effective Against Bowel Disease
Treatment has been completed in a Phase 2 clinical trial of brilacidin for ulcerative proctitis and ulcerative proctosigmoiditis — a study that led to six of the 12 patients' bowel diseases going into remission. Innovation Pharmaceuticals will present the trial results at the Drug Discovery & Therapy World Congress in Boston on July 13. The two inflammatory bowel diseases are collectively known as UP/UPS. "For those of us who have been involved in this trial from the start, it's exciting to see brilacidin perform as well as we thought it would,” Dr. Arthur P. Bertolino, Innovation Pharmaceuticals’ chief medical officer, said in a news release. “The endoscopic evidence we have now gathered on patients is particularly telling. "Brilacidin's unique multi-pronged ability to reduce inflammation, fight infection and heal [gastrointestinal] tract mucosa has been impressive, based both on subjective and objective scoring measures,” he added. “It's no surprise to us why we've generated significant excitement regarding brilacidin among patients, healthcare professionals and potential industry partners interested in this truly novel IBD [inflammatory bowel disease] drug candidate. We look forward to sharing the brilacidin UP/UPS data in early July." The six-week trial investigated the effectiveness, safety and drug properties of three doses of brilacidin. Each of the three groups of patients had mild to moderate UP/UPS. Researchers used the Modified Mayo Disease Activity Index (MMDAI) to determine whether patients' remission had been
Subscribe or to access all post and page content.

One comment

  1. Terry Funk says:

    What happened to the phase 3 trial of Brilacidin for staph jnfections or ABBSi. I have information about a patient here in Bend Oregon who is going to die because they have used all of the last resort antibiotics to no effect. If a patient is going to die anyway what would it hurt to treat him with a drug like brilacidin. If it works you have a win win situation.

Leave a Comment

Your email address will not be published. Required fields are marked *