Mutations in INAVA Gene May Increase Risk of IBD, Yale Study Shows

Mutations in INAVA Gene May Increase Risk of IBD, Yale Study Shows
Mutations of the INAVA gene may boost the risk of inflammatory bowel disease (IBD), according to a new study whose findings not only explain the pathological mechanisms underlying IBD, but may also help design new therapies for patients with such mutations. The study, “An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomes,” appeared in The Journal of Clinical Investigation. IBD

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