Asana Reports Positive Preclinical Data of Treatment for Ulcerative Colitis

Asana Reports Positive Preclinical Data of Treatment for Ulcerative Colitis
Asana Medical has announced positive data from a preclinical study using an innovative liquid treatment called Extracellular Matrix Hydrogel (ECMH) for the treatment of ulcerative colitis (UC) and other gastrointestinal diseases. The study, sponsored by Asana, was conducted in partnership with a team led by Dr. Stephen Badylak, MD, PhD, at the University of Pittsburgh’s McGowan Institute for Regenerative Medicine. Published in the Journal of Crohn’s and Colitis, the study is titled “Restoring Mucosal Barrier Function and Modifying Macrophage Phenotype with an Extracellular Matrix Hydrogel: Potential Therapy for Ulcerative Colitis." The preclinical proof-of-concept showed that in an ulcerative colitis mouse model, the nonsurgical and non-pharmacologic ECMH-therapy promoted mucosal regeneration and inhibited inflammation. The therapy was also able to restore the epithelial barrier function, and to reduce stool blood and weight loss. “The study results suggest an alternative to traditional therapies for inflammatory bowel disease," Badylak, lead researcher at McGowan, said in a press release. "The study shows the ability of ECMH to rapidly transform the inflammatory flares of UC into a healing state in this rodent mo
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6 comments

  1. Peter Trahern says:

    This is great news for sufferers of UC, myself being one of them. I hope and pray you are able to carry out successful human clinical tests in 2017 and I pray this is allowed to be given to persons affected to help with this horrible disease. I would like to be informed if possible please of future developments.

    • Tim Bossie says:

      You are exactly right, this is a horrible illness and we hope that researchers are able to make major breakthroughs in the next year! Thank you for the comment and hope you are doing well.

  2. Kathy Dixey says:

    My daughter suffers from Ulcerative colitis and I would love to be kept updated with news of any research which may eventually lead to a cure for this insidious condition

    • Tim Bossie says:

      We are very sorry to hear about your daughter. We do hope she is doing good now. Have you signed up for your newsletter in order to get the latest articles as they are posted? Or, you can also Like our Facebook page to keep updated.

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