Medication Seen to Help Prevent Post-Surgery Relapse in Crohn’s Patients Who Smoke

Medication Seen to Help Prevent Post-Surgery Relapse in Crohn’s Patients Who Smoke
Smoking long has been associated with an increased relapse risk for patients with Crohn's disease. But results of a new trial indicate that the immunosupressive medication mercaptopurine (Purinethol)  has a greater effect on patients who continue to smoke after having intestinal resection surgery. The benefit of the drug in preventing relapses was negligible in nonsmokers, who probably could be managed by close monitoring without the need for drug therapy. Results of the study are published in Lancet Gastr
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