Crohn’s Disease with Cognitive Impairments Linked to Systemic Inflammation, Poor Sleep Quality

Crohn’s Disease with Cognitive Impairments Linked to Systemic Inflammation, Poor Sleep Quality
Patients with Crohn's disease often have subtle cognitive impairment with slower response times compared to people without the disease, according to a recent study developed at the Monash University and Department of Gastroenterology and Hepatology in Australia. The study, "Cognitive impairment in Crohn’s disease is associated with systemic inflammation, symptom burden and sleep disturbance," published in the United European Gastroenterology Journal, shows that cognitive difficulties in Crohn's disease patients are strongly associated with increased systemic inflammation, and might be caused by indirect disease effects such as disease duration, anxiety, and sleep disturbances. Patients with Crohn's disease, one of the two main forms of inflammatory bowel disease (IBD), have a variety of effects on health and normal function beyond classic symptoms, like abdominal pain and diarrhea. These patients frequently complain of difficulty in concentrating and though cloudiness, but these symptoms are often ignored by clinicians. Identifying decrements in cognitive function, even subtle ones, is important as they may lead to increased risk of car or workplace accidents. But few studies have reported changes in cognitive function in patients with chronic diseases like Crohn's. The research team here sought to compare the cognitive function in Crohn's patients and identify specific disease- and patient-related factors that could be associated with a decrease in cognitive function. They enrolled 41 patients with Crohn's and 31 healthy people, who were assessed using the Subtle Cognitive Impai
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