Study on Diet as Tool in Crohn’s Disease Funded by $2.5M PCORI Award

Study on Diet as Tool in Crohn’s Disease Funded by $2.5M PCORI Award
Dr. James Lewis, M.D., MSCE, professor of medicine and epidemiology at the Perelman School of Medicine, is leading a national research study at the University of Pennsylvania on behalf of the Crohn’s & Colitis Foundation of America (CCFA). The study focuses on diet as a tool for managing Crohn’s disease symptoms, and has been approved to receive a Patient-Centered Outcomes Research Institute’s (PCORI) funding award of $2.5 million. Crohn’s is a chronic inflammatory bowel disease (IBD) with no known cure. It currently affects more than 500,000 Americans. The therapies that do exist are not fully effective, and are also associated with several significant side effects. For IBD patients, diet can be a constant challenge. While the symptoms are not caused by particular foods, certain foods might exacerbate some symptoms in some patients. The study will assess the effectiveness of the carbohydrate diet and the Mediterranean-style diet to induce remission in Crohn’s disease patients. The study is the result of a patient-generated research question posed through CCFA’s patient-powered research network for CCFA Partners. “There is little scientific evidence to guide how patients with Crohn’s should modify their diet.  Because of this, patients and their physicians face substantial uncertainty about the best diet for Crohn’s,” said Lewis, senior scholar and principal investigator of the study, in a press release. “This study will open the door to a more holistic treatment of Crohn
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