4. Use of certain medications

This might increase the risk of developing IBD. Studies have been carried out that show increased risks of IBD among people who use isotretinoin for acne treatment. Also, the use of pain killers and pain relievers (aspirin, ibuprofen,naproxen, etc.) could contribute to the formation of gastrointestinal ulcers, which complicates IBD. Hence, proper advice from a physician is necessary.