Good Gut Health May Depend on a Few Good Microbes

Good Gut Health May Depend on a Few Good Microbes
In a recent study published in the journal Cell Host & Microbe, a team of researchers from the University of Oregon (UO) discovered that strength in numbers does not hold true for intestinal microbes, and that, in fact, a minority population of the right type might hold the key to regulating a good health. An implicit assumption of microbiome profiling for diagnostic purposes is that the proportional representation of different taxa determine host phenotypes. To test this hypothesis, in the study titled “Individual Members of the Microbiota Disproportionately Modulate Host Innate Immune Responses, Annah S. Rolig, study lead author and a postdoctoral researcher in the UO's Institute of Molecular Biology, and colleagues colonized gnotobiotic zebrafish (zebrafish that are either germ-free or have only certain strains of microorganisms) with zebrafish-derived bacterial isolates. They then measured bacterial abundance and host neutrophil immune response. The team reported that one particular bacterial species, called Vibrio, drew numerous neutrophils, indicating a rapid inflammatory response. Shewanella, conversely, was found to barely trigger an immune response when inserted into a second germ-free fish. And when both species were introduced into a third germ-free fish, in a ratio of 90% Vibr
Subscribe or to access all post and page content.

One comment

  1. Majeed Aldamah says:

    yes it is progress each day ,but till now we don’t find
    any PRACTICAL solution for IBD ,IBS and others that not specified yet or not related to IBD ,IBS. Believe me most
    of these diseases come from food raw and processed )that produced by companies looking for huge profits because they make genetic deviation and Hermon’s to plant and animals. they looking for quantity not quality .It must be for GOV.to change and added new food laws for these companies. The consumers(misery people)have no option to chose food because all offered food at markets (processed or raw even so called organic )is bad so what they chose??, they chose the less bad one My kind Regards

Leave a Comment

Your email address will not be published. Required fields are marked *