Pfizer Reports Favorable Results on Oral Tofacitinib for Ulcerative Colitis

Pfizer Reports Favorable Results on Oral Tofacitinib for Ulcerative Colitis
Pfizer recently released the top-line results from two Phase III induction studies of twice-daily tofacitinib (10 mg tablets) for ulcerative colitis, within the Oral Clinical Trials for tofAcitinib in ulceratiVE colitis (OCTAVE) global program. According to the report, both clinical trials were successful at meeting specified primary endpoints, as determined by the number of patients treated with the drug who have achieved remission after 8 weeks compared to those who were given a placebo. “We are encouraged by the results of the OCTAVE induction studies as ulcerative colitis is a chronic, and at times debilitating, disease that can be difficult to treat” said the senior vice president and head of Global Medical Affairs, Global Innovative Pharmaceuticals Business, Pfizer Inc, Rory O’Connor, MD in a press release. “Pfizer remains committed to advancing the science of Janus kinase inhibition and enhancing understanding of tofacitinib, the first in this new class of medications being investigated for ulcerative colitis. We look forward to sharing the results of our ongoing Phase 3 maintenance study OCTAVE Sustain, when available, which will provide further information on tofacitinib in ulcerative colitis.” Pfizer also reported tofacitinib did not induce any untoward side effects, with recently-reported incidences holding similarities to those already noted in past studies with the drug. The findings from both OCTAVE Induction I and OCTAVE Induction II will be analyzed in detail to establish tofac
Subscribe or to access all post and page content.

Leave a Comment

Your email address will not be published. Required fields are marked *