Bioelectronic Low-Level Electric Pulse Reduces Systemic Inflammation in Diseases Such as Crohn’s Disease

Bioelectronic Low-Level Electric Pulse Reduces Systemic Inflammation in Diseases Such as Crohn’s Disease
In a new study entitled “Single-pulse and unidirectional electrical activation of the cervical vagus nerve reduces tumor necrosis factor in endotoxemia,” scientists discovered that a low-level electrical stimulation of body’s vagus nerve reduces systemic inflammation. These findings unveil the therapeutical value of bioelectronic medicine in inflammatory diseases such as Crohn's disease. The study was published in the Bioelectronic Medicine journal. The body’s inflammatory reflex is controlled by the vagus nerve, however, scientists did not know which vagus nerve fibers controlled the inflammatory reflex. The vagus nerve, also known as cranial nerve X, is the longest of the cranial nerves and is part of the involuntary nervous system, thereby controlling unconscious body procedures such as keeping the heart rate constant and controlling food digestion. In this new research, a team of scientists at The Feinstein Institute for Medical Research, together with researchers of the North Shore-LIJ Health System (one of the largest integrated health systems in the United States), and SetPoint Medical Inc. (a biomedical technology company developing implantable neuromodulation devices to treat debilitating inflammatory diseases) investigated the role of vagus nerve fiber stimulation in reducing inflammation. They performed studies in both mice and
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