Mutated T Cell Superenhancers Drive Autoimmune Diseases Like IBD

Mutated T Cell Superenhancers Drive Autoimmune Diseases Like IBD
In a new study entitled “Super-enhancers delineate disease-associated regulatory nodes in T cells,” researchers discovered gene alterations characteristic of autoimmune diseases, such as inflammatory bowel disease or rheumatoid arthritis, are found in genome regions called super-enhancers. The study was published in the journal Nature. Autoimmune diseases are characterized by an exaggerated immune response of the body against one’s

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