SICUS, MRE, CE are Effective Imaging Techniques for Crohn’s Disease in Children, Comparative Study Shows

SICUS, MRE, CE are Effective Imaging Techniques for Crohn’s Disease in Children, Comparative Study Shows
A research team led by Salvatore Cucciara from the Paediatric Gastroenterology and Liver Unit at the Sapienza University of Rome, Italy recently conducted a prospective comparison blinded study on 25 patients recruited from a Tertiary center for pediatric inflammatory bowel disease. The researchers aimed to evaluate sensitivity, specificity, and accuracy of three different imaging methods, specifically, magnetic resonance enterography (MRE), small-intestine contrast US (SICUS), and capsule endoscopy (CE) in the diagnosis of pediatric small bowel in Chohn’s disease. In the study titled, "Magnetic resonance enterography, small-intestine contrast US, and capsule endoscopy to evaluate the small bowel in pediatric Crohn’s disease: a prospective, blinded, comparison study" recently published in the journal Gastrointestinal Endoscopy, the research team compared each imaging method with a standard method for upper small-bowel imaging, and with ileocolonoscopy for the terminal ileum. All patients participating the study had ileocolonoscopy, MRE, SICUS, and CE for a total period of 7 days. For each imaging method, examination of the small-bowel was separated in 3 sections: jejunum, proximal and mid ileum, and terminal ileum. Results revealed that in the jejunum, the sensitivity of SICUS and CE was 92%, higher than MRE (75%), and the specificity of CE was significantly lower than that of MRE. In the proximal and mid ileum, results showed that MRE and CE had higher sensitivity (100%) than SICUS (80%), but CE showed to be less specific. Lastly, in the terminal ileum, results revealed that SICUS and MRE were more sensitive than CE (94% versus 81%, respectively), however CE was more specific. Based on these results, the researchers concluded that all SICUS, MRE,
Subscribe or to access all post and page content.