Top 14 IBD Stories of ’14

Top 14 IBD Stories of ’14
Inflammatory bowel disease (IBD), a disease that includes both ulcerative colitis and Crohn's disease, is a debilitating disease that affects people worldwide. These inflammatory, autoimmune conditions strike the digestive tract, and still pose major unmet medical needs for those diagnosed with them. However, doctors, scientists and biotech companies have been working to reduce the burden of IBD on patients and have made tremendous strides in 2014. These are the top 14 IBD articles of 2014 from IBD News Today: #14. "Rare Mouth Ulcer Might Indicate Crohn’s Disease" A new possible marker for Crohn’s disease has been identified in a recent study entitled, “Buccal localization of Crohn’s disease with long-term infliximab therapy: a case report,” the presence of Cheilitis granulomatosa lesions in the mouth. The symptom is characterized by chronic swelling of the lips and ulceration due to granulomatous inflammation, and is often associated with Melkersson-Rosenthal syndrome, however, it can also be a unique early manifestation of Crohn’s disease. #13. "Obesity Triggers Autoimmune Diseases Like Crohn’s Disease, Study Says" Obesity plays a major role in triggering and also prolonging autoimmune diseases due to the presence of adipokines in the system, as found by Prof. Yehuda Shoenfeld, the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases at Tel Aviv University. Autoimmune diseases such as Crohn’s disease and multiple sclerosis result from the immune system attacking its own body, and obesity triggers a breakdown of the body’s protective self-tolerance, which creates the ideal opportunity for these types of diseases to evolve. #12. "Celltrion Healthcare Presents Clinical Data Showing That Inflammatory Bowel Disease
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