SetPoint Starts Trial on Bioelectronic Therapy for Crohn’s Disease

SetPoint Starts Trial on Bioelectronic Therapy for Crohn’s Disease

setpoint-medicalSetPoint Medical, a biotech company developing therapies for inflammatory bowel diseases (IBD), announced that it is now evaluating safety and efficacy for its novel treatment for Crohn's disease. The announcement was made by the gastroenterologists responsible for the trial at the annual “Advances in Inflammatory Bowel Diseases” clinical and research conference hosted by the Crohn’s & Colitis Foundation in Orlando, Florida.

The Valencia, California-based company will conduct the trial with patients suffering from moderately-to-severely active Crohn’s despite treatment with a tumor necrosis factor (TNF) antagonist drug, and it will be held at five different research centers in Europe. The investigators will stimulate the patients' vagus nerve with an implanted device in order to activate the natural inflammatory reflex of the body, and induce the production of the systemic anti-inflammatory effect.

“Despite recent advances in therapy for Crohn’s most patients do not achieve full disease control and many who are adequately controlled seek alternatives to standard drug treatments” explained the coordinating investigator for the study, Geert D'Haens, who is a Profess

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