Scientists Create First Mini Human Stomach Models in Laboratory

Scientists Create First Mini Human Stomach Models in Laboratory
mini stomachScientists recently made a significant breakthrough in the field of gastroenterological research and development by successfully creating the first three-dimensional human stomach tissue, which can serve as a miniature stomach model to aid more comprehensive studies into the development of diseases, and ultimately change how treatments are developed and how public health crises are addressed. Lead investigator Jim Wells, Ph.D., is a scientist at the division of Developmental Biology and Endocrinology at Cincinnati Children’s Hospital Medical Center. He and fellow researchers explained in their report in the journal Nature, dated October 29, 2014, that the achievement was made possible by human pluripotent stem cells (hPSCs). Together with other investigators from the University of Cincinnati College of Medicine, they were able to create gastric organoids or "mini-stomachs," which facilitated further study on H. pylori infections -- one of the primary causes of peptic ulcer disease and stomach cancer. Through this new development researchers will be able to model and examine even the
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