Opioid Use May Contribute to Imbalances in the Gut and Spur Inflammation, Studies Find

Opioid Use May Contribute to Imbalances in the Gut and Spur Inflammation, Studies Find
Extended use of opioids promotes imbalances in the gut microbiome and triggers changes that worsen inflammation in the intestine, according to results of studies in a mouse model of colitis and tissue samples from Crohn's disease patients. The results were shared recently in an abstract, “Prescription opioids induce gut dysbiosis and exacerbate inflammatory bowel disease,” published in Gastroenterology. Hydromorphone (sold under the brand name Dilaudid, among others) is the most common opioid prescribed for patients with moderate-to-severe pain due to inflam
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