Artificial Sweetener Splenda Found to Worsen Symptoms of Crohn’s Disease in New Mouse Study

Artificial Sweetener Splenda Found to Worsen Symptoms of Crohn’s Disease in New Mouse Study
The artificial sweetener Splenda (sucralose maltodextrin) was recently found to worsen gut inflammation in mice with Crohn’s disease, while no effects were seen in mice without the condition. The investigation, led by researchers from Case Western Reserve University School of Medicine, found that, during a six-week period, Splenda promoted “bad” bacteria and intestinal inflammation. These findings could have implications for humans with inflammatory bowel diseases (IBDs). In recent self-assessment dietary surveys, about 10 percent of patients living with IBDs reported that “sugary foods” worsen the severity of their symptoms and trigger flare-ups. Other epidemiological studies have also shown a strong association between the use of artificial sweeteners and an increased risk for IBD. Findings from the study, titled “The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn’s Disease–Like Ileitis.”were published in the journal Inflammatory Bowel Diseases. The findings revealed increases in the numbers of proteobacteria, a large group of microbes, in the intestines of mice that drank water supplemented with Splenda. Half of
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One comment

  1. CM Cortez says:

    I experience extreme diarrhea for a long period of time until I realized Sucralose (Splenda), Stevia, and any other fake sugar other than Aspartame caused this. It was violent and caused my body to go into a form of shock. I have to read every label now including candy, gum, soft drinks, etc.

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